Fibrillin 1 antibody

Catalog No. ABIN2461618

This Rabbit Polyclonal antibody specifically detects Fibrillin 1 in WB and ELISA. It exhibits reactivity toward Human and Dog.

Quick Overview for Fibrillin 1 antibody (ABIN2461618)

Target: Fibrillin 1 (FBN1)

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrillin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Fibrillin 1 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBN1.

Application Details

Application Notes: FBN1 antibody can be used for detection of FBN1 by ELISA at 1:1562500. FBN1 antibody can be used for detection of FBN1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FBN1 antibody at -20 °C.

Target Details for Fibrillin 1

Target: Fibrillin 1 (FBN1)

Alternative Name: FBN1

Background: FBN1 is a member of the fibrillin family. FBN1 is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.

Molecular Weight: 21 kDa, 312 kDa

Gene ID: 2200

UniProt: Q75N89

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome