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MSH2 antibody

MSH2 Reactivity: Human, Mouse, Dog, Zebrafish (Danio rerio) WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2462390
  • Target See all MSH2 Antibodies
    MSH2 (Mismatch Repair Protein 2 (MSH2))
    Reactivity
    • 79
    • 40
    • 19
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Dog, Zebrafish (Danio rerio)
    Host
    • 75
    • 18
    • 1
    Rabbit
    Clonality
    • 71
    • 24
    Polyclonal
    Conjugate
    • 60
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MSH2 antibody is un-conjugated
    Application
    • 59
    • 36
    • 28
    • 22
    • 21
    • 14
    • 13
    • 12
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MSH2.
    Top Product
    Discover our top product MSH2 Primary Antibody
  • Application Notes
    MSH2 antibody can be used for detection of MSH2 by ELISA at 1:62500. MSH2 antibody can be used for detection of MSH2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store MSH2 antibody at -20 °C.
  • Target
    MSH2 (Mismatch Repair Protein 2 (MSH2))
    Alternative Name
    MSH2 (MSH2 Products)
    Synonyms
    COCA1 antibody, FCC1 antibody, HNPCC antibody, HNPCC1 antibody, LCFS2 antibody, AI788990 antibody, wu:fc06b02 antibody, wu:fc13e09 antibody, zgc:55333 antibody, ATMSH2 antibody, MUTS homolog 2 antibody, msh2 antibody, mutS homolog 2 antibody, mutS homolog 2 (E. coli) antibody, MUTS homolog 2 antibody, mutS homolog 2 L homeolog antibody, MutS protein homolog 2 antibody, MSH2 antibody, Msh2 antibody, msh2 antibody, msh2.L antibody
    Background
    MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.
    Molecular Weight
    64 kDa, 105 kDa
    Gene ID
    4436
    UniProt
    P43246
    Pathways
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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