HAO1 antibody

Catalog No. ABIN2462589

Product Details anti-HAO1 Antibody

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HAO1.

Application Details

Application Notes: HAO1 antibody can be used for detection of HAO1 by ELISA at 1:1562500. HAO1 antibody can be used for detection of HAO1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HAO1 antibody at -20 °C.

Target Details for HAO1

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Alternative Name: HAO1 (HAO1 Products)

Synonyms: hao1 antibody, GOX antibody, GOX1 antibody, HAOX1 antibody, Gox1 antibody, XDH1 antibody, Hao-1 antibody, hydroxyacid oxidase 1 antibody, hydroxyacid oxidase (glycolate oxidase) 1 antibody, hydroxyacid oxidase (glycolate oxidase) 1 L homeolog antibody, hydroxyacid oxidase 1, liver antibody, CpipJ_CPIJ013711 antibody, THEYE_A0075 antibody, hao1 antibody, HAO1 antibody, hao1.L antibody, Hao1 antibody

Background: Subcellular location of HAO1 is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.

Molecular Weight: 41 kDa

Gene ID: 54363

NCBI Accession: NP_060015

UniProt: Q9UJM8

Pathways: Monocarboxylic Acid Catabolic Process