HAO1 antibody
Quick Overview for HAO1 antibody (ABIN7205123)
Target
See all HAO1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Mouse Anti-HAO1 Monoclonal Antibody
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Specificity
- The antibody detects endogenous HAO1 protein.
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Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Recombinant Protein
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Isotype
- IgG1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000-2000,IF 1:200,IHC 1:50-300
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
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Alternative Name
- HAO1
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Background
- HAO1 (hydroxyacid oxidase 1) is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
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Molecular Weight
- 41kD
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Gene ID
- 54363
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UniProt
- Q9UJM8
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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