FKBP6 antibody

Catalog No. ABIN2462654

Product Details anti-FKBP6 Antibody

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FKBP6.

Application Details

Application Notes: FKBP6 antibody can be used for detection of FKBP6 by ELISA at 1:1562500. FKBP6 antibody can be used for detection of FKBP6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FKBP6 antibody at -20 °C.

Target Details for FKBP6

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Alternative Name: FKBP6 (FKBP6 Products)

Background: FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.

Molecular Weight: 53 kDa, 53 kDa

Gene ID: 8468

NCBI Accession: NP_003593

UniProt: O75344

Pathways: M Phase