FKBP6 antibody

Catalog No. ABIN2462654

The Rabbit Polyclonal anti-FKBP6 antibody has been validated for WB, ELISA and IHC. It is suitable to detect FKBP6 in samples from Human, Mouse, Rat and Dog.

Quick Overview for FKBP6 antibody (ABIN2462654)

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FKBP6 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FKBP6.

Application Details

Application Notes: FKBP6 antibody can be used for detection of FKBP6 by ELISA at 1:1562500. FKBP6 antibody can be used for detection of FKBP6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FKBP6 antibody at -20 °C.

Target Details for FKBP6

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Alternative Name: FKBP6

Background: FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.

Molecular Weight: 53 kDa, 53 kDa

Gene ID: 8468

NCBI Accession: NP_003593

UniProt: O75344

Pathways: M Phase