LMAN1 antibody
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- Target See all LMAN1 Antibodies
- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
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Reactivity
- Human, Mouse, Rat, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LMAN1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LMAN1.
- Top Product
- Discover our top product LMAN1 Primary Antibody
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- Application Notes
- LMAN1 antibody can be used for detection of LMAN1 by ELISA at 1:1562500. LMAN1 antibody can be used for detection of LMAN1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store LMAN1 antibody at -20 °C.
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- Target
- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
- Alternative Name
- LMAN1 (LMAN1 Products)
- Synonyms
- ERGIC-53 antibody, ERGIC53 antibody, F5F8D antibody, FMFD1 antibody, MCFD1 antibody, MR60 antibody, gp58 antibody, 2610020P13Rik antibody, AI326273 antibody, AU043785 antibody, C730041J05 antibody, P58 antibody, p58 antibody, LMAN1 antibody, cpx-iii antibody, cpxiii antibody, lman1 antibody, wu:fc54c09 antibody, wu:fi36e01 antibody, Xp58 antibody, lman1-a antibody, lectin, mannose binding 1 antibody, lectin, mannose-binding, 1 antibody, complexin 3 antibody, lectin, mannose binding 1 S homeolog antibody, LMAN1 antibody, Lman1 antibody, cplx3 antibody, lman1 antibody, lman1.S antibody
- Background
- LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
- Molecular Weight
- 54 kDa
- Gene ID
- 3998
- NCBI Accession
- NP_005561
- UniProt
- P49257
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