GTF2A1L antibody

Catalog No. ABIN2463375

Product Details anti-GTF2A1L Antibody

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2A1L antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTF2A1L.

Application Details

Application Notes: GTF2A1L antibody can be used for detection of GTF2A1L by ELISA at 1:1562500. GTF2A1L antibody can be used for detection of GTF2A1L by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GTF2A1L antibody at -20 °C.

Target Details for GTF2A1L

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Alternative Name: GTF2A1L (GTF2A1L Products)

Synonyms: ALF antibody, 1700011N16Rik antibody, Alf antibody, Gtf2a1lf antibody, general transcription factor IIA subunit 1 like antibody, general transcription factor IIA, 1-like antibody, general transcription factor 2A subunit 1 like antibody, GTF2A1L antibody, Gtf2a1l antibody

Background: The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Molecular Weight: 52 kDa

Gene ID: 11036

NCBI Accession: NP_006863

UniProt: Q9UNN4