HIST2H2AA3 antibody

Catalog No. ABIN2463431

The Rabbit Polyclonal anti-HIST2H2AA3 antibody is suitable to detect HIST2H2AA3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for HIST2H2AA3 antibody (ABIN2463431)

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST2H2AA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HIST2H2AA3 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HIST2H2AA3.

Application Details

Application Notes: HIST2H2AA3 antibody can be used for detection of HIST2H2AA3 by ELISA at 1:12500. HIST2H2AA3 antibody can be used for detection of HIST2H2AA3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HIST2H2AA3 antibody at -20 °C.

Target Details for HIST2H2AA3

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Alternative Name: HIST2H2AA3

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AA3 is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 14 kDa

Gene ID: 8337

NCBI Accession: NP_003507

UniProt: Q7L7L0

Pathways: Telomere Maintenance