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Caveolin 3 antibody

CAV3 Reactivity: Human, Dog WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2463712
  • Target See all Caveolin 3 (CAV3) Antibodies
    Caveolin 3 (CAV3)
    Reactivity
    • 40
    • 23
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Dog
    Host
    • 38
    • 2
    • 1
    Rabbit
    Clonality
    • 30
    • 11
    Polyclonal
    Conjugate
    • 20
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This Caveolin 3 antibody is un-conjugated
    Application
    • 18
    • 9
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CAV3.
    Top Product
    Discover our top product CAV3 Primary Antibody
  • Application Notes
    CAV3 antibody can be used for detection of CAV3 by ELISA at 1:12500. CAV3 antibody can be used for detection of CAV3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store CAV3 antibody at -20 °C.
  • Target
    Caveolin 3 (CAV3)
    Alternative Name
    CAV3 (CAV3 Products)
    Synonyms
    LGMD1C antibody, LQT9 antibody, VIP-21 antibody, VIP21 antibody, AI385751 antibody, Cav-3 antibody, M-cav antibody, caveolin-3 antibody, im:6902906 antibody, zgc:109710 antibody, LOC733765 antibody, CAV3 antibody, cav3 antibody, caveolin 3 antibody, caveolin-3 antibody, CAV3 antibody, Cav3 antibody, cav3 antibody, LOC733765 antibody, cav-3 antibody
    Background
    CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
    Molecular Weight
    17 kDa
    Gene ID
    859
    NCBI Accession
    NP_001225
    UniProt
    P56539
    Pathways
    Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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