GABRP antibody

Catalog No. ABIN2463744

Product Details anti-GABRP Antibody

Target: GABRP (gamma-aminobutyric Acid (GABA) A Receptor, pi (GABRP))

Reactivity: Mouse, Human, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRP.

Application Details

Application Notes: GABRP antibody can be used for detection of GABRP by ELISA at 1:1562500. GABRP antibody can be used for detection of GABRP by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GABRP antibody at -20 °C.

Target Details for GABRP

Target: GABRP (gamma-aminobutyric Acid (GABA) A Receptor, pi (GABRP))

Alternative Name: GABRP (GABRP Products)

Synonyms: gamma-aminobutyric acid type A receptor pi subunit antibody, gamma-aminobutyric acid (GABA) A receptor, pi antibody, Gabrp antibody, GABRP antibody

Background: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded GABRP is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.

Molecular Weight: 51 kDa

Gene ID: 2568

NCBI Accession: NP_055026

UniProt: O00591