GDI2 antibody

Catalog No. ABIN2463746

The Rabbit Polyclonal anti-GDI2 antibody is suitable to detect GDI2 in samples from Human and Dog. It has been validated for ELISA and WB.

Quick Overview for GDI2 antibody (ABIN2463746)

Target: GDI2 (GDP Dissociation Inhibitor 2 (GDI2))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDI2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-GDI2 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GDI2.

Application Details

Application Notes: GDI2 antibody can be used for detection of GDI2 by ELISA at 1:312500. GDI2 antibody can be used for detection of GDI2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GDI2 antibody at -20 °C.

Target Details for GDI2

Target: GDI2 (GDP Dissociation Inhibitor 2 (GDI2))

Alternative Name: GDI2

Background: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.

Molecular Weight: 51 kDa

Gene ID: 2665

NCBI Accession: NP_001485

UniProt: P50395