TCF4 antibody

Catalog No. ABIN2463811

Product Details anti-TCF4 Antibody

Target: TCF4 (Transcription Factor 4 (TCF4))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF4.

Application Details

Application Notes: TCF4 antibody can be used for detection of TCF4 by ELISA at 1:62500. TCF4 antibody can be used for detection of TCF4 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TCF4 antibody at -20 °C.

Target Details for TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Alternative Name: TCF4 (TCF4 Products)

Synonyms: E2-2 antibody, ITF-2 antibody, ITF2 antibody, PTHS antibody, SEF-2 antibody, SEF2 antibody, SEF2-1 antibody, SEF2-1A antibody, SEF2-1B antibody, TCF-4 antibody, bHLHb19 antibody, 5730422P05Rik antibody, ASP-I2 antibody, E2.2 antibody, ITF-2b antibody, ME2 antibody, MITF-2A antibody, MITF-2B antibody, TFE antibody, Tcf-4 antibody, TCF7L2 antibody, XE2 antibody, Xtcf-4 antibody, Xtcf4 antibody, e2-A antibody, tcf-4 antibody, transcription factor 4 antibody, transcription factor 4 S homeolog antibody, TCF4 antibody, Tcf4 antibody, tcf4 antibody, tcf4.S antibody

Background: TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well.TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well. TCF4 is known to produce multiple transcripts, however as the complete structure is only known for the transcript that encodes the b isoform, that is the variant presented here.

Molecular Weight: 71 kDa

Gene ID: 6925

NCBI Accession: NP_003190

UniProt: P15884

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus