Fibulin 5 antibody (truncated)

Catalog No. ABIN2464054

Product Details anti-Fibulin 5 Antibody

Target: Fibulin 5 (FBLN5)

Binding Specificity: truncated

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibulin 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: Ni-NTA purified truncated recombinant Fibulin 5 expressed in E. Coli strain BL21 (DE3).

Clone: 3F8D5

Isotype: IgM

Application Details

Application Notes: Western Blot:1:500 - 1:2000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: Fibulin 5 monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for Fibulin 5

Target: Fibulin 5 (FBLN5)

Alternative Name: Fibulin5 (FBLN5 Products)

Synonyms: zgc:103575 antibody, FBLN5 antibody, MGC108414 antibody, Fibulin-5 antibody, DKFZp469K0327 antibody, ADCL2 antibody, ARCL1A antibody, ARMD3 antibody, DANCE antibody, EVEC antibody, FIBL-5 antibody, UP50 antibody, A55 antibody, fibulin 5 antibody, fbln5 antibody, FBLN5 antibody, Fbln5 antibody

Background: Fibulin 5(FBLN5), with 448-amino acid protein (about 50 kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

Gene ID: 10516

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome