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HCK antibody (truncated)
HCK
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
3D12E10
unconjugated
Product Details anti-HCK Antibody
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Target
See all HCK Antibodies
HCK
(Hemopoietic Cell Kinase (HCK))
Binding Specificity
All epitopes for HCK antibodies
truncated
Reactivity
All reactivities for HCK antibodies
Human
Host
All hosts for HCK antibodies
Mouse
Clonality
All clonalities for HCK antibodies
Monoclonal
Conjugate
All conjugates for HCK antibodies
This HCK antibody is un-conjugated
Application
All applications for HCK antibodies
Western Blotting (WB), ELISA
Immunogen
Ni-NTA purified truncated recombinant HCK-His fusion protein is expressed in E. Coli strain BL21 (DE3).
Clone
3D12E10
Isotype
IgG1
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Discover our top product HCK Primary Antibody
Alternatives
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Application Details
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Application Notes
Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage
-20 °C
Storage Comment
HCK monoclonal antibody can be stored at -20 °C, stable for one year.
Target Details for HCK
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Target
HCK
(Hemopoietic Cell Kinase (HCK))
Alternative Name
HCK (HCK Products )
Synonyms
laloo antibody, HCK antibody, MGC107870 antibody, JTK9 antibody, p59Hck antibody, p61Hck antibody, AI849071 antibody, Bmk antibody, Hctk antibody, p56Hck antibody, HCK proto-oncogene, Src family tyrosine kinase L homeolog antibody, HCK proto-oncogene, Src family tyrosine kinase antibody, hemopoietic cell kinase antibody, hck.L antibody, HCK antibody, hck antibody, Hck antibody
Background
Hemopoietic cell kinase.The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
Gene ID
3055
UniProt
P08631
Pathways
Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Regulation of Actin Filament Polymerization , CXCR4-mediated Signaling Events , Thromboxane A2 Receptor Signaling
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