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TYRO3 antibody (truncated)

This anti-TYRO3 antibody is a Mouse Monoclonal antibody detecting TYRO3 in WB, ELISA and IF. Suitable for Human.
Catalog No. ABIN2464119

Quick Overview for TYRO3 antibody (truncated) (ABIN2464119)

Target

See all TYRO3 Antibodies
TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Reactivity

  • 48
  • 13
  • 7
  • 4
Human

Host

  • 30
  • 22
  • 3
  • 1
Mouse

Clonality

  • 27
  • 24
  • 2
  • 1
Monoclonal

Conjugate

  • 45
  • 3
  • 3
  • 1
  • 1
  • 1
This TYRO3 antibody is un-conjugated

Application

  • 36
  • 24
  • 17
  • 9
  • 9
  • 8
  • 8
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone

1C10E8-9A3F2
  • Binding Specificity

    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    truncated

    Immunogen

    Ni-NTA purified truncated recombinant TYRO3 expressed in E. Coli strain BL21 (DE3).

    Isotype

    IgG1
  • Application Notes

    Western Blot:1:500 - 1:2,000
    IF:1:50 - 1:200
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.

    Restrictions

    For Research Use only
  • Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    Storage

    -20 °C

    Storage Comment

    TYRO3 monoclonal antibody can be stored at -20 °C, stable for one year.
  • Target

    TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

    Alternative Name

    TYRO3

    Background

    Tyrosine-protein kinase (TYRO3) belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

    Gene ID

    7301

    UniProt

    Q06418

    Pathways

    RTK Signaling
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