Huntingtin antibody (N-Term)

Catalog No. ABIN2464133

The Rabbit Polyclonal anti-Huntingtin antibody has been validated for IHC, WB and ELISA. It is suitable to detect Huntingtin in samples from Human, Rat and Mouse.

Quick Overview for Huntingtin antibody (N-Term) (ABIN2464133)

Target: Huntingtin (HTT)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Huntingtin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-Huntingtin Antibody

Binding Specificity: N-Term

Purification: Affinity Purified

Immunogen: A synthetic peptide corresponding to the N-terminus.

Isotype: IgG

Application Details

Application Notes: ELISA, Western (immuno) blotting, Immunostaining (in testing)

Restrictions: For Research Use only

Handling

Target Details for Huntingtin

Target: Huntingtin (HTT)

Alternative Name: Huntington Protein

Background: Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington s disease protein is ~350 kDa in size and is localized in the brain.

Gene ID: 3064

UniProt: P42858

Pathways: PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport