JAK2 antibody (pTyr372)

Catalog No. ABIN2464134

This anti-JAK2 antibody is a Rabbit Polyclonal antibody detecting JAK2 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for JAK2 antibody (pTyr372) (ABIN2464134)

Target: JAK2 (Janus Kinase 2 (JAK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-JAK2 Antibody

Binding Specificity: pTyr372

Purification: Affinity Purified

Immunogen: A synthetic peptide corresponding to the pY372 region.

Isotype: IgG

Application Details

Application Notes: ELISA, Western (immuno) blotting, Immunostaining (in testing)

Restrictions: For Research Use only

Handling

Target Details for JAK2

Target: JAK2 (Janus Kinase 2 (JAK2))

Alternative Name: Janus Kinase 2

Background: Janus Kinase 2 (JAK2) is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins

Gene ID: 12643404

UniProt: O60674

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response