GPR3 antibody (N-Term)

Catalog No. ABIN2467014

The Rabbit Polyclonal anti-GPR3 antibody (ABIN2467014) specifically detects GPR3 in ELISA and IHC. The antibody is reactive with Human, Monkey, Gibbon and Gorilla samples.

Quick Overview for GPR3 antibody (N-Term) (ABIN2467014)

Target: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Reactivity: Human, Monkey, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-GPR3 Antibody

Binding Specificity: N-Term

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CASKIN2 (53 % ), INPPL1 (47 %).

Purification: Immunoaffinity Chromatography

Immunogen: GPR3 antibody was raised against a peptide located in the N-Terminal extracellular domain of GPR3 (Human).

Application Details

Application Notes: GPR3 antibody can be used in ELISA, and immunohistochemistry starting at 3 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: GPR3 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for GPR3

Target: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Alternative Name: GPR3

Background: GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging (Ledent et al. 2005).

Gene ID: 2827

UniProt: P46089

Pathways: cAMP Metabolic Process