G3BP1 antibody (AA 132-350)

Catalog No. ABIN2467818

The Chicken Polyclonal anti-G3BP1 antibody (ABIN2467818) specifically detects G3BP1 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for G3BP1 antibody (AA 132-350) (ABIN2467818)

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This G3BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-G3BP1 Antibody

Binding Specificity: AA 132-350

Purification: Antigen affinity-purified

Application Details

Application Notes: G3BP(M-219) antibody can be used for the detection of G3BP(M-219) by Western blot, may also work for IHC and ICC.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Preservative: Without preservative

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: G3BP antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Target Details for G3BP1

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Alternative Name: G3BP

Background: Ras-GTPase-activating protein SH3-domain-binding protein, GAP binding protein, RasGAP-associated endoribonuclease G3BP. This protein is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Molecular Weight: 52.2 kDa (calculated)

Gene ID: 10146

NCBI Accession: NP_005745

UniProt: Q13283

Pathways: SARS-CoV-2 Protein Interactome