TNC antibody (AA 18-175)
Quick Overview for TNC antibody (AA 18-175) (ABIN2467941)
Target
See all TNC AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 18-175
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Purification
- Immunoaffinity Purified
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Application Notes
- Tenascin antibody can be used for the detection of Tenascin by Western Blot.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline. No preservatives added.
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Preservative
- Without preservative
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Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage
- 4 °C/-20 °C
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Storage Comment
- TNC antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- TNC (Tenascin C (TNC))
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Alternative Name
- TNC
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Background
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FUNCTION: SAM (substrate-adhesion molecule) that appears to inhibit cell migration. May play a role in supporting the growth of epithelial tumors. Is a ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
SUBUNIT: Hexameric. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4. -
Molecular Weight
- 240.9 kDa (calculated)
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Gene ID
- 3371
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NCBI Accession
- NP_002151
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UniProt
- P24821
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Pathways
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
Target
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