DUSP6 antibody (AA 135-280)

Catalog No. ABIN2468007

This anti-DUSP6 antibody is a Chicken Polyclonal antibody detecting DUSP6 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for DUSP6 antibody (AA 135-280) (ABIN2468007)

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This DUSP6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DUSP6 Antibody

Binding Specificity: AA 135-280

Purification: Immunoaffinity Purified

Application Details

Application Notes: Dual specificity phosphatase 6 antibody can be used for the detection of Dual specificity phosphatase 6 by Western Blot.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Preservative: Without preservative

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: DUSP6 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Target Details for DUSP6

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Alternative Name: DUSP6

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This protein product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm.

Molecular Weight: 15.1 kDa (calculated)

Gene ID: 1848

NCBI Accession: NP_001937

UniProt: Q16828

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades