SGK1 antibody (AA 211-431)

Catalog No. ABIN2468035

This Chicken Polyclonal antibody specifically detects SGK1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SGK1 antibody (AA 211-431) (ABIN2468035)

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This SGK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGK1 Antibody

Binding Specificity: AA 211-431

Purification: Immunoaffinity Purified

Application Details

Application Notes: Serine/threonine-protein kinase Sgk1 antibody can be used for the detection of Serine/threonine-protein kinase Sgk1 by Western Blot.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Preservative: Without preservative

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: SGK antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Target Details for SGK1

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Alternative Name: SGK

Background: FUNCTION: Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, Kv1.3, or EAAT1.

Molecular Weight: 49 kDa (calculated)

Gene ID: 6446

NCBI Accession: NP_005618

UniProt: O00141

Pathways: MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway