XCR1 antibody (3rd Extracellular Domain)

Catalog No. ABIN2469272

Product Details anti-XCR1 Antibody

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Binding Specificity: 3rd Extracellular Domain

Reactivity: Human, Gorilla, Gibbon

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XCR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: XCR1 antibody was raised against a peptide located in the 3rd extracellular domain of XCR1 (Human).

Application Details

Application Notes: XCR1 antibody can be used in immunohistochemistry starting at 5 μg/mL, and immunofluorescence.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: XCR1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for XCR1

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Alternative Name: XCR1 (XCR1 Products)

Synonyms: CCXCR1-L antibody, XCR1 antibody, CCXCR1 antibody, GPR5 antibody, Ccxcr1 antibody, Gpr5 antibody, mXcr1 antibody, X-C motif chemokine receptor 1 antibody, chemokine (C motif) receptor 1a, duplicate 1 antibody, chemokine (C motif) receptor 1 antibody, XCR1 antibody, xcr1a.1 antibody, Xcr1 antibody

Background: CCXCR1 is a Chemokine Receptor expressed in lymphotactin-responsive leukocyte cells. The viral macrophage inflammatory protein-II, vMIP-II (but not vMIP-I), has been found to be an antagonist of lymphotactin activity at CCXCR1. The CCXCR1 gene is located near the genes for C-C chemokine receptor 9 and SIV/HIV receptor Bonzo on chromosome 3. CCXCR1 is associated with inflammatory and immunological responses by regulating the trafficking of T and B lymphocytes and neutrophils. The up-regulation of CCXCR1 in peripheral T cells is correlated with the inflammatory process observed in Crohns disease.

Gene ID: 2829

UniProt: P46094