FZD5 antibody (N-Term)

Catalog No. ABIN2469394

Product Details anti-FZD5 Antibody

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Binding Specificity: N-Term

Reactivity: Human, Cow, Dog, Rabbit, Pig, Monkey, Gorilla, Gibbon

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: Frizzled 5 antibody was raised against a peptide located in the N-Terminal extracellular domain of Frizzled 5 (Human).

Application Details

Application Notes: Frizzled 5 antibody can be used in immunohistochemistry starting at 20 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: Frizzled 5 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for FZD5

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Alternative Name: Frizzled 5 (FZD5 Products)

Synonyms: C2orf31 antibody, HFZ5 antibody, 5330434N09Rik antibody, AI427138 antibody, Fz-5 antibody, Fz5 antibody, mFz5 antibody, Xfz5 antibody, frizzled5 antibody, frizzled5a antibody, fz5 antibody, fzd5-A antibody, fz2 antibody, fz8c antibody, fzd8c antibody, zg02 antibody, frizzled class receptor 5 antibody, frizzled class receptor 5 S homeolog antibody, FZD5 antibody, Fzd5 antibody, fzd5.S antibody, fzd5 antibody

Background: FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway.

Gene ID: 7855

UniProt: Q13467

Pathways: WNT Signaling