FZD5 antibody (N-Term)

Catalog No. ABIN2469394

This Rabbit Polyclonal antibody specifically detects FZD5 in ELISA and IHC. It exhibits reactivity toward Human, Cow, Dog, Rabbit, Pig, Monkey, Gibbon and Gorilla.

Quick Overview for FZD5 antibody (N-Term) (ABIN2469394)

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Reactivity: Human, Cow, Dog, Rabbit, Pig, Monkey, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-FZD5 Antibody

Binding Specificity: N-Term

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: Frizzled 5 antibody was raised against a peptide located in the N-Terminal extracellular domain of Frizzled 5 (Human).

Application Details

Application Notes: Frizzled 5 antibody can be used in immunohistochemistry starting at 20 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: Frizzled 5 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for FZD5

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Alternative Name: Frizzled 5

Background: FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway.

Gene ID: 7855

UniProt: Q13467

Pathways: WNT Signaling