CERK antibody (Internal Region)

Catalog No. ABIN2469403

This Rabbit Polyclonal antibody specifically detects CERK in IHC. It exhibits reactivity toward Human, Monkey and Gibbon.

Quick Overview for CERK antibody (Internal Region) (ABIN2469403)

Target: CERK (Ceramide Kinase (CERK))

Reactivity: Human, Monkey, Gibbon

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CERK antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CERK Antibody

Binding Specificity: Internal Region

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: Ceramide Kinase antibody was raised against a peptide located near the internal domain of Ceramide Kinase (Human).

Application Details

Application Notes: Ceramide Kinase antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: Ceramide Kinase antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for CERK

Target: CERK (Ceramide Kinase (CERK))

Alternative Name: Ceramide Kinase

Background: CERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.

Gene ID: 64781

UniProt: Q8TCT0