PDE6A antibody (N-Term)

Catalog No. ABIN2469463

This Rabbit Polyclonal antibody specifically detects PDE6A in IHC. It exhibits reactivity toward Human, Mouse, Rat, Hamster, Monkey, Gibbon and Gorilla.

Quick Overview for PDE6A antibody (N-Term) (ABIN2469463)

Target: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Reactivity: Human, Mouse, Rat, Hamster, Monkey, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PDE6A Antibody

Binding Specificity: N-Term

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: PDE6A antibody was raised against a peptide located in the N-Terminal region of PDE6A (Human).

Application Details

Application Notes: PDE6A antibody can be used in ELISA, Western Blot starting at 1 - 2 μg/mL, immunohistochemistry starting at 10 μg/mL, immunocytochemistry, and immunoprecipitation starting at 1 - 2 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: PDE6A antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for PDE6A

Target: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Alternative Name: PDE6A

Background: Phosphodiesterase 6A, a catalytic subunit of the photoreceptor phosphodiesterase, has been shown to affect functioning of eye retina as the alpha subunit of the heterotetrameric rod photoreceptor. Mutations in PDE6A have been identified as a cause of autosomal recessive retinitis pigmentosa.

Gene ID: 5145

UniProt: P16499

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction