EPHX2 antibody (Internal Region)

Catalog No. ABIN2469511

This Rabbit Polyclonal antibody specifically detects EPHX2 in IHC. It exhibits reactivity toward Human and Gorilla.

Quick Overview for EPHX2 antibody (Internal Region) (ABIN2469511)

Target: EPHX2 (Epoxide Hydrolase 2, Cytoplasmic (EPHX2))

Reactivity: Human, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPHX2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-EPHX2 Antibody

Binding Specificity: Internal Region

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except RHOBTB2 (44 % ), RHOBTB1 (44 %).

Purification: Immunoaffinity Chromatography

Immunogen: EPHX2 antibody was raised against a peptide located near the internal domain of EPHX2 (Human).

Application Details

Application Notes: EPHX2 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: EPHX2 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for EPHX2

Target: EPHX2 (Epoxide Hydrolase 2, Cytoplasmic (EPHX2))

Alternative Name: EPHX2

Background: Soluble Epoxide Hydrolase (sEH) also known as cytosolic Epoxide Hydrolase is a phase I xenobiotic-metabolizing enzyme that converts epoxyeicosatrienoic acids (EETs) into their corresponding dihydroxyeicosatrienoic acids (DHETs). EETs are thought to be involved in vascular tone, ion channel regulation, mitogenesis and cell signaling. DHETs have, in general, less biological activity then EETs and are more readily excreted, thus hydration of EETs by sEH maybe a means of attenuating or eliminating their activity.sEHs have been identified in many tissues including liver, kidney, adrenal, pancreatic islets, gi tract and vascular smooth muscle.

Gene ID: 2053

UniProt: P34913