TBK1 antibody (AA 563-577)

Catalog No. ABIN2469637

This Mouse Monoclonal antibody specifically detects TBK1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit, Dog, Monkey, Pig, Horse, Hamster, Gibbon and Gorilla.

Quick Overview for TBK1 antibody (AA 563-577) (ABIN2469637)

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Monkey, Pig, Horse, Hamster, Gibbon, Gorilla

Host: Mouse

Clonality: Monoclonal

Conjugate: This TBK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 108A429

Product Details anti-TBK1 Antibody

Binding Specificity: AA 563-577

Purification: Protein G Column

Immunogen: TBK1 monoclonal antibody was raised against a synthetic peptide corresponding to amino acids 563 - 577 of TBK1 (Human).

Isotype: IgG1 kappa

Application Details

Application Notes: TBK1 antibody can be used in ELISA starting at 1:10000, and immunohistochemistry starting at 1:200 - 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: TBK1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Alternative Name: TBK1

Background: TBK1, also known as NF-kappa-B-activating kinase (NAK), is an IKAPPAB type protein kinase. TBK1 protein contains a N-terminal kinase domain and two putative coiled-coil regions in the C-terminal region. It has been shown to associate with TANK and TRAF2 in a TBK1-TANK-TRAF2 signaling complex, which is believed to function upstream of the IKK complex in the TRAF-mediated activation of NF-kappaB.

Gene ID: 29110

UniProt: Q9UHD2

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome