CD74 antibody

Catalog No. ABIN2472420

Cited in 2+ publications. The Mouse Monoclonal anti-CD74 antibody (Clone Bu45) (ABIN2472420) specifically detects CD74 in FACS, IF, IP, IHC (fro) and Func. The antibody is reactive with Human samples.

Quick Overview for CD74 antibody (ABIN2472420)

Target: CD74 (HLA-DR-gamma (CD74))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD74 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: Bu45

Product Details anti-CD74 Antibody

Characteristics: Purified IgG

Purification: Purified

Immunogen: B lymphoblastoid cell line HFB1.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-CD74 antibody (ABIN2472420)

Lapaque, Jahnke, Trowsdale, Kelly: "The HLA-DRalpha chain is modified by polyubiquitination." in: The Journal of biological chemistry, Vol. 284, Issue 11, pp. 7007-16, (2009) (PubMed).

Beswick, Bland, Suarez, Barrera, Fan, Reyes: "Helicobacter pylori binds to CD74 on gastric epithelial cells and stimulates interleukin-8 production." in: Infection and immunity, Vol. 73, Issue 5, pp. 2736-43, (2005) (PubMed).

Target Details for CD74

Target: CD74 (HLA-DR-gamma (CD74))

Alternative Name: CD74

Gene ID: 972

UniProt: P04233

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints