GZMA antibody

Catalog No. ABIN2473883

The Mouse Monoclonal anti-GZMA antibody has been validated for WB and IHC (p). It is suitable to detect GZMA in samples from Human. There are 2+ publications available.

Quick Overview for GZMA antibody (ABIN2473883)

Target: GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GZMA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GA6

Product Details anti-GZMA Antibody

Characteristics: Purified IgG

Purification: Purified

Immunogen: Recombinant human Granzyme A

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-GZMA antibody (ABIN2473883)

Meade, Wilson, Holmes, de Wynter, Brett, Straszynski, Ballard, Trapani, McDermott, Cook: "Proteolytic activation of the cytotoxic phenotype during human NK cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 803-13, (2009) (PubMed).

Mahrus, Craik: "Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells." in: Chemistry & biology, Vol. 12, Issue 5, pp. 567-77, (2005) (PubMed).

Target Details for GZMA

Target: GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Alternative Name: GRANZYME A

Gene ID: 3001

UniProt: P12544

Pathways: Apoptosis