APP antibody (AA 737-751)

Catalog No. ABIN2477429

The Rabbit Polyclonal anti-APP antibody has been validated for WB and IHC (p). It is suitable to detect APP in samples from Human, Mouse and Rat. There are 2+ publications available.

Quick Overview for APP antibody (AA 737-751) (ABIN2477429)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-APP Antibody

Binding Specificity: AA 737-751

Immunogen: Synthetic peptide corresponding to amino acids 737-751 of human APP

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

References for anti-APP antibody (ABIN2477429)

Zhang, Gao, Dai, Meng, Tu, Yan: "IGF-1 reduces BACE-1 expression in PC12 cells via activation of PI3-K/Akt and MAPK/ERK1/2 signaling pathways." in: Neurochemical research, Vol. 36, Issue 1, pp. 49-57, (2010) (PubMed).

Yan, Xiong, Luo, Struble, Clough: "beta-Secretase expression in normal and functionally deprived rat olfactory bulbs: inverse correlation with oxidative metabolic activity." in: The Journal of comparative neurology, Vol. 501, Issue 1, pp. 52-69, (2007) (PubMed).

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: AMYLOID PRECURSOR PROTEIN

Gene ID: 351

UniProt: P05067

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour