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CD11b antibody

ITGAM Reactivity: Rat FACS, IHC (fro), Func Host: Mouse Monoclonal ED7 unconjugated
Catalog No. ABIN2478200
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 265
    • 176
    • 65
    • 31
    • 20
    • 19
    • 17
    • 14
    • 11
    • 10
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    Rat
    Host
    • 147
    • 111
    • 106
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 269
    • 95
    • 2
    Monoclonal
    Conjugate
    • 121
    • 41
    • 29
    • 27
    • 19
    • 9
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is un-conjugated
    Application
    • 279
    • 86
    • 81
    • 79
    • 59
    • 44
    • 37
    • 25
    • 22
    • 19
    • 14
    • 14
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    Specificity
    This antibody recognises a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. Like ED8, ED7 recognises small ramified microglia in the central nervous system. No other cell types are positive for ED7, except for the cilia of the bronchus epithelium. The recognised antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules (CD11b/CD18). ED7 and ED8 may recognise closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.
    Characteristics
    Purified IgG
    Purification
    Purified
    Immunogen
    Rat spleen cell homogenate
    Clone
    ED7
    Isotype
    IgG1
    Top Product
    Discover our top product ITGAM Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    CD11b (ITGAM Products)
    Background
    Synonyms: INTEGRIN ALPHA M CHAIN, MAC-1
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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