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CD11b antibody (FITC)

This Rat Monoclonal antibody specifically detects CD11b in FACS. It exhibits reactivity toward Human, Mouse and Rabbit and has been mentioned in 3+ publications.
Catalog No. ABIN2478229

Quick Overview for CD11b antibody (FITC) (ABIN2478229)

Target

See all CD11b (ITGAM) Antibodies
CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity

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Human, Mouse, Rabbit

Host

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Rat

Clonality

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Monoclonal

Conjugate

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This CD11b antibody is conjugated to FITC

Application

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Flow Cytometry (FACS)

Clone

M1-70-15
  • Cross-Reactivity

    Human, Rabbit

    Characteristics

    Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC)

    Immunogen

    T cell enriched splenocytes from B10 mice

    Isotype

    IgG2b
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL
  • Lebson, Nash, Kamath, Herber, Carty, Lee, Li, Szekeres, Jinwal, Koren, Dickey, Gottschall, Morgan, Gordon: "Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 29, pp. 9651-8, (2010) (PubMed).

    Zhang, Nei, Dougherty: "A p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-alpha." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 38, pp. 12844-55, (2010) (PubMed).

    Patel, Harrison: "Membrane ruffles capture C3bi-opsonized particles in activated macrophages." in: Molecular biology of the cell, Vol. 19, Issue 11, pp. 4628-39, (2008) (PubMed).

  • Target

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    Alternative Name

    CD11b

    Background

    Synonyms: INTEGRIN ALPHA M CHAIN, MAC-1

    Gene ID

    16409

    UniProt

    P05555

    Pathways

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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