CD25 antibody (PE)

Catalog No. ABIN2479448

There are 3+ publications for this product available. The Mouse Monoclonal anti-CD25 antibody is suitable to detect CD25 in samples from Dog. It has been validated for FACS.

Quick Overview for CD25 antibody (PE) (ABIN2479448)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD25 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: P4A10

Product Details anti-CD25 Antibody (PE)

Characteristics: Purified IgG conjugated to R. Phycoerythrin (RPE)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

References for anti-CD25 antibody (PE) (ABIN2479448)

Abrams, Hwang, Lesnikova, Gass, Wayner, Castilla-Llorente, Georges, Nash: "A novel monoclonal antibody specific for canine CD25 (P4A10): selection and evaluation of canine Tregs." in: Veterinary immunology and immunopathology, Vol. 135, Issue 3-4, pp. 257-65, (2010) (PubMed).

Rissetto, Rindt, Selting, Villamil, Henry, Reinero: "Cloning and expression of canine CD25 for validation of an anti-human CD25 antibody to compare T regulatory lymphocytes in healthy dogs and dogs with osteosarcoma." in: Veterinary immunology and immunopathology, Vol. 135, Issue 1-2, pp. 137-45, (2010) (PubMed).

Finn, Ozelo, Sabatino, Franck, Merricks, Crudele, Zhou, Kazazian, Lillicrap, Nichols, Arruda: "Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy." in: Blood, Vol. 116, Issue 26, pp. 5842-8, (2010) (PubMed).

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: CD25

Background: Synonyms: IL-2R ALPHA CHAIN

Gene ID: 403870

UniProt: O62802

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation