CD25 antibody

Catalog No. ABIN2479449

The Mouse Monoclonal anti-CD25 antibody has been validated for FACS. It is suitable to detect CD25 in samples from Human. There are 3+ publications available.

Quick Overview for CD25 antibody (ABIN2479449)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD25 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: MEM-181

Product Details anti-CD25 Antibody

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

References for anti-CD25 antibody (ABIN2479449)

Thorborn, Pomeroy, Isohanni, Perry, Peters, Vyakarnam: "Increased sensitivity of CD4+ T-effector cells to CD4+CD25+ Treg suppression compensates for reduced Treg number in asymptomatic HIV-1 infection." in: PLoS ONE, Vol. 5, Issue 2, pp. e9254, (2010) (PubMed).

Cutler, Limbani, Girdlestone, Navarrete: "Umbilical cord-derived mesenchymal stromal cells modulate monocyte function to suppress T cell proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 11, pp. 6617-23, (2010) (PubMed).

Prager, Staffler, Majdic, Säemann, Godár, Zlabinger, Stockinger: "Induction of hyporesponsiveness and impaired T lymphocyte activation by the CD31 receptor:ligand pathway in T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 4, pp. 2364-71, (2001) (PubMed).

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: CD25

Background: Synonyms: IL-2R ALPHA CHAIN

Gene ID: 3559

UniProt: P01589

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation