TLR3 antibody

Catalog No. ABIN2479742

The Rat Monoclonal anti-TLR3 antibody has been validated for FACS and IF. It is suitable to detect TLR3 in samples from Mouse. There are 3+ publications available.

Quick Overview for TLR3 antibody (ABIN2479742)

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TLR3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 11F8

Product Details anti-TLR3 Antibody

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-TLR3 antibody (ABIN2479742)

Azuma, Ebihara, Oshiumi, Matsumoto, Seya: "Cross-priming for antitumor CTL induced by soluble Ag + polyI:C depends on the TICAM-1 pathway in mouse CD11c(+)/CD8?(+) dendritic cells." in: Oncoimmunology, Vol. 1, Issue 5, pp. 581-592, (2012) (PubMed).

Jelinek, Leonard, Price, Brown, Meyer-Manlapat, Goldsmith, Wang, Venzon, Epstein, Segal: "TLR3-specific double-stranded RNA oligonucleotide adjuvants induce dendritic cell cross-presentation, CTL responses, and antiviral protection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 4, pp. 2422-9, (2011) (PubMed).

McCartney, Vermi, Gilfillan, Cella, Murphy, Schreiber, Murphy, Colonna: "Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells." in: The Journal of experimental medicine, Vol. 206, Issue 13, pp. 2967-76, (2009) (PubMed).

Target Details for TLR3

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Alternative Name: CD283

Background: Synonyms: TLR3

Gene ID: 142980

UniProt: Q99MB1

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades