TLR4 antibody

Catalog No. ABIN2479746

This Mouse Monoclonal antibody specifically detects TLR4 in WB, FACS and IP. It exhibits reactivity toward Human, Dog, Pig, Guinea Pig and Rhesus Monkey and has been mentioned in 2+ publications.

Quick Overview for TLR4 antibody (ABIN2479746)

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivity: Human, Dog, Pig, Guinea Pig, Rhesus Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: HTA125

Product Details anti-TLR4 Antibody

Cross-Reactivity: Dog (Canine), Guinea Pig, Pig (Porcine), Rhesus Monkey

Characteristics: Purified IgG

Purification: Purified

Immunogen: Ba/F3 cell line expressing TLR4 (CD284)

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-TLR4 antibody (ABIN2479746)

Foster, Lea, Preshaw, Taylor: "Pivotal advance: vasoactive intestinal peptide inhibits up-regulation of human monocyte TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages." in: Journal of leukocyte biology, Vol. 81, Issue 4, pp. 893-903, (2007) (PubMed).

Jiang, Akashi, Miyake, Petty: "Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 7, pp. 3541-4, (2000) (PubMed).

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: CD284

Background: Synonyms: TLR4

Gene ID: 7099

UniProt: O00206

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins