TLR4 antibody

Catalog No. ABIN2479755

This anti-TLR4 antibody is a Mouse Monoclonal antibody detecting TLR4 in WB, FACS, IP and Func. Suitable for Human, Dog, Pig, Guinea Pig and Rhesus Monkey. This Primary Antibody has been cited in 2+ publications.

Quick Overview for TLR4 antibody (ABIN2479755)

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivity: Human, Dog, Pig, Guinea Pig, Rhesus Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Clone: HTA125

Product Details anti-TLR4 Antibody

Cross-Reactivity: Dog (Canine), Guinea Pig, Pig (Porcine), Rhesus Monkey

Characteristics: Purified IgG

Endotoxin Level: Low endotoxin

Immunogen: Ba/F3 cell line expressing TLR4 (CD284).

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-TLR4 antibody (ABIN2479755)

Foster, Lea, Preshaw, Taylor: "Pivotal advance: vasoactive intestinal peptide inhibits up-regulation of human monocyte TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages." in: Journal of leukocyte biology, Vol. 81, Issue 4, pp. 893-903, (2007) (PubMed).

Jiang, Akashi, Miyake, Petty: "Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 7, pp. 3541-4, (2000) (PubMed).

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: CD284

Background: Synonyms: TLR4

Gene ID: 7099

UniProt: O00206

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins