TLR4 antibody (PE)

Catalog No. ABIN2479757

The Mouse Monoclonal anti-TLR4 antibody has been validated for FACS. It is suitable to detect TLR4 in samples from Human, Dog, Pig, Guinea Pig and Rhesus Monkey. There are 2+ publications available.

Quick Overview for TLR4 antibody (PE) (ABIN2479757)

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivity: Human, Dog, Pig, Guinea Pig, Rhesus Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR4 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: HTA125

Product Details anti-TLR4 Antibody (PE)

Cross-Reactivity: Dog (Canine), Guinea Pig, Pig (Porcine), Rhesus Monkey

Characteristics: Purified IgG conjugated to R. Phycoerythrin (RPE)

Immunogen: Ba/F3 cell line expressing TLR4 (CD284).

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

References for anti-TLR4 antibody (PE) (ABIN2479757)

Foster, Lea, Preshaw, Taylor: "Pivotal advance: vasoactive intestinal peptide inhibits up-regulation of human monocyte TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages." in: Journal of leukocyte biology, Vol. 81, Issue 4, pp. 893-903, (2007) (PubMed).

Jiang, Akashi, Miyake, Petty: "Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 7, pp. 3541-4, (2000) (PubMed).

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: CD284

Background: Synonyms: TLR4

Gene ID: 7099

UniProt: O00206

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins