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GRIN2B antibody (AA 20-271) (Atto 488)

GRIN2B Reactivity: Rat WB, IHC, IF, IP, ICC, AA Host: Mouse Monoclonal S59 Atto 488
Catalog No. ABIN2483207
  • Target See all GRIN2B Antibodies
    GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
    Binding Specificity
    • 33
    • 30
    • 24
    • 22
    • 22
    • 20
    • 16
    • 10
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-271
    Reactivity
    • 195
    • 180
    • 152
    • 30
    • 27
    • 24
    • 10
    • 10
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Rat
    Host
    • 205
    • 37
    • 1
    Mouse
    Clonality
    • 207
    • 36
    Monoclonal
    Conjugate
    • 107
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GRIN2B antibody is conjugated to Atto 488
    Application
    • 196
    • 65
    • 65
    • 65
    • 46
    • 40
    • 31
    • 24
    • 23
    • 18
    • 16
    • 10
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Antibody Array (AA)
    Specificity
    Detects ~166 kDa. No cross-reactivity against NR2A.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 20-271 (extracellular N-terminus) of rat NR2B
    Clone
    S59
    Isotype
    IgG2b
    Top Product
    Discover our top product GRIN2B Primary Antibody
  • Application Notes
    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2483207 was sufficient for detection of NR2B in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
    Alternative Name
    NR2B (GRIN2B Products)
    Synonyms
    NMDAR2B antibody, GluN2B antibody, MRD6 antibody, NR2B antibody, hNR3 antibody, nmdar2b antibody, nr2b antibody, AW490526 antibody, Nmdar2b antibody, glutamate ionotropic receptor NMDA type subunit 2B antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog antibody, glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody, GRIN2B antibody, Grin2b antibody, grin2b.L antibody
    Background
    NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (1). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain, NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics (2).
    Gene ID
    24410
    NCBI Accession
    NP_036706
    UniProt
    Q00960
    Pathways
    Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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