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GRIN2B antibody (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B) (AA 20-271) (FITC) Primary Antibody

GRIN2B Reactivity: Human, Mouse, Rat AA, ICC, IF, IHC, IP, WB Host: Mouse Monoclonal S59-36 FITC
Catalog No. ABIN2483217
$526.50
Plus shipping costs $45.00
100 μg
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  • Target
    GRIN2B
    Binding Specificity
    • 44
    • 34
    • 30
    • 28
    • 19
    • 16
    • 16
    • 15
    • 15
    • 15
    • 12
    • 11
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-271
    Reactivity
    • 240
    • 224
    • 200
    • 17
    • 13
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 226
    • 55
    • 7
    Mouse
    Clonality
    • 233
    • 55
    Monoclonal
    Conjugate
    • 111
    • 16
    • 12
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    This GRIN2B antibody is conjugated to FITC
    Application
    • 173
    • 91
    • 90
    • 77
    • 63
    • 60
    • 36
    • 32
    • 30
    • 27
    • 22
    • 22
    • 21
    • 4
    • 2
    • 2
    • 1
    Antibody Array (AA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
    Specificity
    Detects ~166 kDa. No cross-reactivity against NR2A.
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 20-271 (extracellular N-terminus) of rat NR2B
    Clone
    S59-36
    Isotype
    IgG2b
  • Application Notes
    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2483217 was sufficient for detection of NR2B in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    GRIN2B
    Alternative Name
    NR2B (GRIN2B Antibody Abstract)
    Synonyms
    NMDAR2B, GluN2B, MRD6, NR2B, hNR3, nmdar2b, nr2b, AW490526, Nmdar2b, glutamate ionotropic receptor NMDA type subunit 2B, glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog, glutamate receptor, ionotropic, NMDA2B (epsilon 2), GRIN2B, Grin2b, grin2b.L
    Background
    NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (1). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain, NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics (2).
    Gene ID
    24410
    NCBI Accession
    NP_036706
    UniProt
    Q00960
    Pathways
    Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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