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MDC1 antibody (N-Term) (Atto 488)

MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 Atto 488
Catalog No. ABIN2484142
  • Target See all MDC1 Antibodies
    MDC1 (Mdc1 (MDC1))
    Binding Specificity
    • 21
    • 16
    • 15
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 60
    • 53
    • 16
    • 12
    • 11
    • 2
    • 1
    • 1
    Mouse
    Host
    • 50
    • 36
    Mouse
    Clonality
    • 50
    • 36
    Monoclonal
    Conjugate
    • 30
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MDC1 antibody is conjugated to Atto 488
    Application
    • 66
    • 30
    • 14
    • 13
    • 13
    • 12
    • 12
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.
    Cross-Reactivity
    Chimpanzee, Cow, Human, Mouse
    Purification
    Protein G Purified
    Immunogen
    GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
    Clone
    P2B11
    Isotype
    IgG1
    Top Product
    Discover our top product MDC1 Primary Antibody
  • Application Notes
    • WB (1:2000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    0.5 μg/ml of ABIN2484142 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    MDC1 (Mdc1 (MDC1))
    Alternative Name
    MDC1 (MDC1 Products)
    Synonyms
    6820401C03 antibody, AA413496 antibody, Nfbd1 antibody, mKIAA0170 antibody, NFBD1 antibody, mediator of DNA damage checkpoint 1 antibody, mediator of DNA-damage checkpoint 1 antibody, Mdc1 antibody, MDC1 antibody
    Background
    MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
    Gene ID
    240087
    NCBI Accession
    NP_001010833
    UniProt
    Q5PSV9
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