POGLUT1 antibody (AA 201-300) (HRP)

Catalog No. ABIN2559510

The Rabbit Polyclonal anti-POGLUT1 antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect POGLUT1 in samples from Mouse.

Quick Overview for POGLUT1 antibody (AA 201-300) (HRP) (ABIN2559510)

Target: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POGLUT1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-POGLUT1 Antibody (HRP)

Binding Specificity: AA 201-300

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KTELC1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for POGLUT1

Target: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Alternative Name: KTELC1

Background:

Synonyms: Rumi, CLP46, MDSRP, C3orf9, KTELC1, MDS010, hCLP46, KDELCL1, Protein O-glucosyltransferase 1, CAP10-like 46 kDa protein, KTEL motif-containing protein 1, Myelodysplastic syndromes relative protein, O-glucosyltransferase Rumi homolog, hRumi, Protein O-xylosyltransferase, POGLUT1, UNQ490/PRO1006

Background: Dual specificity glycosyltransferase. Catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to EGF repeats, such as those found in F7, F9 and NOTCH2, on the consensus sequence C-X-S-X-P-C. Positively regulates Notch signaling without affecting Notch ligand binding.

Gene ID: 56983

UniProt: Q8NBL1

Pathways: Notch Signaling