POGLUT1 antibody (AA 160-280)

Catalog No. ABIN7269673

This Rabbit Polyclonal antibody specifically detects POGLUT1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for POGLUT1 antibody (AA 160-280) (ABIN7269673)

Target: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POGLUT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-POGLUT1 Antibody

Binding Specificity: AA 160-280

Purpose: POGLUT1 Rabbit pAb

Sequence: MYPAWTFWEG GPAVWPIYPT GLGRWDLFRE DLVRSAAQWP WKKKNSTAYF RGSRTSPERD PLILLSRKNP KLVDAEYTKN QAWKSMKDTL GKPAAKDVHL VDHCKYKYLF NFRGVAASFR F

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-280 of human POGLUT1 (NP_689518.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for POGLUT1

Target: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Alternative Name: POGLUT1

Background: This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],C3orf9,CLP46,KDELCL1,KTELC1,LGMD2Z,MDS010,MDSRP,Rumi,hCLP46,POGLUT1,Cell Biology & Developmental Biology,POGLUT1

Gene ID: 56983

UniProt: Q8NBL1

Pathways: Notch Signaling