Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DHRS2 antibody (AA 61-160)

DHRS2 Reactivity: Human, Mouse, Rat WB, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2559682
  • Target See all DHRS2 Antibodies
    DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 61-160
    Reactivity
    • 41
    • 21
    • 18
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    • 1
    Rabbit
    Clonality
    • 40
    • 1
    Polyclonal
    Conjugate
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DHRS2 antibody is un-conjugated
    Application
    • 40
    • 19
    • 17
    • 12
    • 12
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DHRS2
    Isotype
    IgG
    Top Product
    Discover our top product DHRS2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))
    Alternative Name
    DHRS2 (DHRS2 Products)
    Synonyms
    DHRS2 antibody, HEP27 antibody, SDR25C1 antibody, 5430405K24Rik antibody, Hep27 antibody, dehydrogenase/reductase 4 antibody, dehydrogenase/reductase 2 antibody, dehydrogenase/reductase member 2 antibody, DHRS4 antibody, DHRS2 antibody, Dhrs2 antibody
    Background

    Synonyms: HEP27, SDR25C1, Dehydrogenase/reductase SDR family member 2, mitochondrial, Dicarbonyl reductase HEP27, Protein D, DHRS2

    Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

    Gene ID
    10202
    UniProt
    Q13268
    Pathways
    C21-Steroid Hormone Metabolic Process
You are here:
Support