APP antibody (pThr743)

Catalog No. ABIN2617188

The Rabbit Polyclonal anti-APP antibody has been validated for WB, IHC and IHC (p). It is suitable to detect APP in samples from Human, Mouse, Rat, Dog, Chicken, Pig and Zebrafish (Danio rerio).

Quick Overview for APP antibody (pThr743) (ABIN2617188)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Human, Mouse, Rat, Dog, Chicken, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-APP Antibody

Binding Specificity: pThr743

Specificity: Recognizes endogenous levels of Beta Amyloid (pT743) protein.

Purification: Immunoaffinity purified

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-terminal region of human Beta Amyloid (pT743).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (1:100 - 1:200), WB (1:500 - 1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.3, 0.01 % sodium azide, 30 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to avoid freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot to avoid freeze/thaw cycles.

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: APP / beta Amyloid

Background: Name/Gene ID: APP
Family: Amyloid precursor protein

Synonyms: APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II

Gene ID: 351

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour