CDK6 antibody (AA 291-310)

Catalog No. ABIN2618913

The Rabbit Polyclonal anti-CDK6 antibody has been validated for WB. It is suitable to detect CDK6 in samples from Human, Mouse and Rat.

Quick Overview for CDK6 antibody (AA 291-310) (ABIN2618913)

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDK6 Antibody

Binding Specificity: AA 291-310

Specificity: Expressed in subgranular zone (SGZ) of the hippocampal dentate gyrus (DG) and the subventricular zone (SVZ) of the lateral ventricles whose neural precursor cells (NPC) give rise to dentate granule neurons and olfactory bulb (OB) interneurons, respectively. Expressed in the neuroepithelium of the cerebral cortex of the developing brain. .

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Cdk6(291-310aa AYGALNHPYFQDLERYKDNL), identical to the related rat sequence, and different from the related human sequence by four amino acids.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for CDK6

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Alternative Name: CDK6

Background: Name/Gene ID: CDK6
Subfamily: CDC2/CDK
Family: Protein Kinase

Synonyms: CDK6, CDKN6, Cell division protein kinase 6, Cyclin-dependent kinase 6, Crk2, PLSTIRE

Gene ID: 1021

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases