CRTC2 antibody (AA 595-611)
Quick Overview for CRTC2 antibody (AA 595-611) (ABIN2619526)
Target
See all CRTC2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 595-611
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Specificity
- Most abundantly expressed in the thymus. Present in both B and T-lymphocytes. Highly expressed in HEK293T cells and in insulinomas. High levels also in spleen, ovary, muscle and lung, with highest levels in muscle. Lower levels found in brain, colon, heart, kidney, prostate, small intestine and stomach. Weak expression in liver and pancreas.
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Cross-Reactivity (Details)
- No cross reactivity with other proteins.
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Purification
- Immunogen affinity purified
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human TORC2(595-611aa QDPHTFNHQNLTHCSRH), different from the related rat sequence by three amino acids, and from the related mouse sequence by two amino acids.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Distilled water
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Concentration
- Lot specific
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Buffer
- Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.
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Preservative
- Sodium azide, Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
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- CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
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Alternative Name
- CRTC2 / TORC2
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Background
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Name/Gene ID: CRTC2
Synonyms: CRTC2, Transducer of CREB protein 2, TORC-2, TORC2 -
Gene ID
- 200186
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Pathways
- AMPK Signaling, Carbohydrate Homeostasis
Target
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