CRTC2 antibody

Catalog No. ABIN7384434

The Rabbit Monoclonal anti-CRTC2 antibody is suitable to detect CRTC2 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for CRTC2 antibody (ABIN7384434)

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CRTC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R08-5F2

Product Details anti-CRTC2 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRTC2

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Alternative Name: CREB Regulated Transcription Coactivator 2

Background: CREB regulated transcription coactivator 2,CREB-regulated transcription coactivator 2,CRTC2,CRTC2,RP11-422P24.6,TORC-2,torc2,Transducer of CREB protein 2,Transducer of regulated cAMP response element-binding protein,Transducer of regulated cAMP response element-binding protein (CREB) 2,Transducer of regulated cAMP response element-binding protein 2,Transducer of regulated CREB protein 2,This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. 

Molecular Weight:

Observed_MW: 80kDa

Calculated_MW: 73kDa

Gene ID: 200186

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis