Huntingtin antibody (AA 3106-3121)

Catalog No. ABIN2622233

This Rabbit Polyclonal antibody specifically detects Huntingtin in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Huntingtin antibody (AA 3106-3121) (ABIN2622233)

Target: Huntingtin (HTT)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Huntingtin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Huntingtin Antibody

Binding Specificity: AA 3106-3121

Specificity: Expressed in the brain cortex (at protein level). Widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation. .

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Huntingtin(3106-3121aa ELDRRAFQSVLEVVAA), different from the related mouse and rat sequences by two amino acids.

Isotype: IgG

Application Details

Application Notes: Approved: WB

Usage: Applications and images are for the unconjugated form of this antibody. The conjugated antibody has not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for Huntingtin

Target: Huntingtin (HTT)

Alternative Name: HTT / Huntingtin

Background: Name/Gene ID: HTT
Family: Hungtintin

Synonyms: HTT, Huntingtin, Huntington disease protein, IT15, HD, HD protein

Gene ID: 3064

Pathways: PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport